Quantitative gene expression identifies appropriate cell line models for individual cervical cancer pathways

نویسندگان

  • Mark W Carlson
  • Edward M Marcotte
  • Mark W. Carlson
  • Vishwanath R. Iyer
  • Edward M. Marcotte
چکیده

Like all articles in BMC journals, this peer-reviewed article was published immediately upon acceptance. It can be downloaded, printed and distributed freely for any purposes (see copyright notice below). Articles in BMC journals are listed in PubMed and archived at PubMed Central. For information about publishing your research in BMC journals or any BioMed Central journal, go to http://www.biomedcentral.com/info/authors/ BMC Genomics

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of the effect of methanolic extract of pomegranate peel on cytotoxicity induction and PDGF gene expression in cervical cancer (Hela cell line)

Background & Aim: Extract of pomegranate peel is a potential bioactive substance to combat cancer due to its rich cytotoxic components including polyphenols. This study aimed to identify phytochemical ingredients of pomegranate peel extract and assessed the level of their cytotoxicity on a cervical cancer cell line. In addition, the effect of this extract on expression of a key gene in the proc...

متن کامل

The effect of catechin metabolism derived from intestinal microbiota on Ca SKi cell proliferation

Background & aim: In Iran, cervical cancer is the second leading cause of death in women. Papillomavirus infection is the most important risk factor for the development of cervical cancer. Ca SKi cell is a human cervical carcinoma cell that binds the papillomavirus type 16 virus to its genome. Cactin is a type of phenol and a secondary metabolite of a plant. The purpose of this study was to inv...

متن کامل

Effects of fibromodulin protein expression on NFkB and TGFβ signaling pathways in liver cancer cells

Introduction: The incidence rate of liver cancer is continuously increasing. Currently, gene therapy is applied to improve various medical issues such as cancer treatment approaches. Correspondingly, fibromodulin involves in many biological and physiological processes through interaction with growth factors and signaling pathway receptors. The aim of this study was to investigate the effects of...

متن کامل

Effect of trichostatin A on histone deacetylase 1 (HDAC 1) and CIP/KIP (p21CIP1/WAF1, p27KIP1, and p57KIP2) gene expression, cell growth inhibition and apoptosis induction in lung cancer COR-L105 cell line. Abstract

Effect of trichostatin A on histone deacetylase 1 (HDAC 1) and CIP/KIP (p21CIP1/WAF1, p27KIP1, and p57KIP2) gene expression, cell growth inhibition and apoptosis induction in lung cancer COR-L105 cell line. Abstract Background: Lung cancer is one the leading cause of cancer-related death worldwide, with more than 1.2 million deaths each year. In addition to genetic mutations, epigenetic modif...

متن کامل

THE EFFECT OF QUINACRINE ON THE EXPRESSION OF WNT3A GENE IN MDA-MB 231 AND MCF7 BREAST CANCER CELL LINES

Background & Aims: Triple-negative breast cancer cells refer to any breast cancer that does not express the genes for the estrogen, progesterone, and HER2 receptors. The Wnt signaling pathway is important in the development and progression of various types of cancers. Quinacrine, a derivative of 9-aminoacridine, has been shown to inhibit the growth of several types of cancer cells. In this stud...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2007